Saponin Formosanin C-Induced Ferritinophagy and Ferroptosis in Human Hepatocellular Carcinoma Cells

Ferroptosis, a recently discovered form of iron-dependent cell death, requires an increased level of lipid-reactive oxygen species (ROS). Ferritinophagy, a ferritin degradation pathway, depends on a selective autophagic cargo receptor (NCOA4). By screening various types of natural compounds, formosa...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Pin-Lun Lin, Han-Hsuan Tang, Shan-Ying Wu, Ning-Sing Shaw, Chun-Li Su
Format:	Article
Language:	English
Published:	MDPI AG 2020-07-01
Subjects:	formosanin C hepatocellular carcinoma ferroptosis autophagy ferritinophagy
Online Access:	https://www.mdpi.com/2076-3921/9/8/682