A novel BRAF::PTPRN2 fusion in meningioma: a case report

Abstract Gene fusion events have been linked to oncogenesis in many cancers. However, gene fusions in meningioma are understudied compared to somatic mutations, chromosomal gains/losses, and epigenetic changes. Fusions involving B-raf proto-oncogene, serine/threonine kinase (BRAF) are subtypes of on...

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Bibliographic Details
Published in:Acta Neuropathologica Communications
Main Authors: Nishanth S. Sadagopan, Khizar R. Nandoliya, Mark W. Youngblood, Craig M. Horbinski, Jared T. Ahrendsen, Stephen T. Magill
Format: Article
Language:English
Published: BMC 2023-12-01
Subjects:
BRAF
PTPRN2
Gene Fusion
Meningioma
Chromothripsis
Chromosome 7q
Online Access:https://doi.org/10.1186/s40478-023-01668-w

Internet

https://doi.org/10.1186/s40478-023-01668-w

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