Metabolic and mitochondrial dysregulation in CD4+ T cells from HIV-positive women on combination anti-retroviral therapy.

<h4>Background</h4>For optimal functionality, immune cells require a robust and adaptable metabolic program that is fueled by dynamic mitochondrial activity. In this study, we investigate the metabolic alterations occurring in immune cells during HIV infection and antiretroviral therapy...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Matrona Akiso, Magdalene Ameka, Kewreshini Naidoo, Robert Langat, Janet Kombo, Delories Sikuku, Thumbi Ndung'u, Marcus Altfeld, Omu Anzala, Marianne Mureithi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Online Access:https://doi.org/10.1371/journal.pone.0286436