E670G PCSK9 polymorphism in HeFH & CAD with diabetes: is the bridge to personalized therapy within reach?

ObjectiveTo assess the distribution of PCSK9 E670G genetic polymorphism and PCSK9 levels in patients with Coronary Artery Disease (CAD) and Heterozygous Familial Hypercholesterolemia (HeFH), based on the presence of type 2 Diabetes Mellitus (T2DM).MethodsThe study included 201 patients with chronic...

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Bibliographic Details

Published in:	Frontiers in Clinical Diabetes and Healthcare
Main Authors:	Rano Alieva, Aleksandr Shek, Alisher Abdullaev, Khurshid Fozilov, Shovkat Khoshimov, Guzal Abdullaeva, Dariya Zakirova, Rano Kurbanova, Lilia Kan, Andrey Kim
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Subjects:	heterozygous familial hypercholesterolemia CAD type 2 diabetes mellitus pcsk9 Uzbek population
Online Access:	https://www.frontiersin.org/articles/10.3389/fcdhc.2023.1277288/full