Cyclic and acyclic defensins inhibit human immunodeficiency virus type-1 replication by different mechanisms.

Defensins are antimicrobial peptides expressed by plants and animals. In mammals there are three subfamilies of defensins, distinguished by structural features: alpha, beta and theta. Alpha and beta-defensins are linear peptides with broad anti-microbial activity that are expressed by many mammals i...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Aprille Seidel, Ying Ye, Lesley R de Armas, Maira Soto, William Yarosh, Renee A Marcsisin, Dat Tran, Michael E Selsted, David Camerini
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-03-01
Online Access:	http://europepmc.org/articles/PMC2840026?pdf=render