nSeP: immune and metabolic biomarkers for early detection of neonatal sepsis—protocol for a prospective multicohort study

Introduction Diagnosing neonatal sepsis is heavily dependent on clinical phenotyping as culture-positive body fluid has poor sensitivity, and existing blood biomarkers have poor specificity.A combination of machine learning, statistical and deep pathway biology analyses led to the identification of...

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Bibliographic Details

Published in:	BMJ Open
Main Authors:	Alok Sharma, Daniel White, Claire Smith, Nitin Goel, Amar Asokkumar, Cora Doherty, Siva Oruganti, Sailesh Kotecha, Judith Orme, Robert Andrews, Ian Morris, David Odd, Mallinath Chakraborty, Sarah Edkins, W John Watkins, Rachel Hayward, B. Paul Morgan, Jennifer Calvert, Elisa Smit, Patrícia R S Rodrigues, Angela Hayward, Rebekka Jones, Sian Elliott, Angela Strang, Summia Zaher, Simran Sharma, Marie Craigon, Widad Dantoft, Luke C Davies, Linda Moet, James E McLaren, Samantha Clarkstone, Gareth L Watson, Valerie B O’Donnell, Peter Ghazal
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2021-12-01
Online Access:	https://bmjopen.bmj.com/content/11/12/e050100.full