Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer’s Disease

Abstract The cerebrospinal fluid (CSF) biochemical markers (biomarkers) Amyloidβ 42 (Aβ42), total Tau (T-tau) and Tau phosphorylated at threonine 181 (P-tau181) have proven diagnostic accuracy for mild cognitive impairment and dementia due to Alzheimer’s Disease (AD). In an effort to improve the acc...

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Bibliographic Details

Published in:	Alzheimer’s Research & Therapy
Main Authors:	Oskar Hansson, Sylvain Lehmann, Markus Otto, Henrik Zetterberg, Piotr Lewczuk
Format:	Article
Language:	English
Published:	BMC 2019-04-01
Subjects:	Alzheimer’s Disease Amyloidβ Peptides Aβ42/40 ratio Biomarkers Cerebrospinal Fluid
Online Access:	http://link.springer.com/article/10.1186/s13195-019-0485-0