Distinct impacts of Eda and Edar loss of function on the mouse dentition.

BACKGROUND: The Eda-A1-Edar signaling pathway is involved in the development of organs with an ectodermal origin, including teeth. In mouse, mutants are known for both the ligand, Eda-A1 (Tabby), and the receptor, Edar (Downless). The adult dentitions of these two mutants have classically been consi...

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發表在:PLoS ONE
Main Authors: Cyril Charles, Sophie Pantalacci, Paul Tafforeau, Denis Headon, Vincent Laudet, Laurent Viriot
格式: Article
語言:英语
出版: Public Library of Science (PLoS) 2009-01-01
在線閱讀:http://europepmc.org/articles/PMC2659790?pdf=render