Immune microenvironment of tumor-draining lymph nodes: insights for immunotherapy

Tumor-draining lymph nodes (TDLNs) play a crucial role in modulating tumor immune responses and influencing the efficacy of immunotherapy. However, our current understanding of the microenvironment within these lymph nodes remains limited. Tumors not only impair the anti-tumor activity of CD8+ T cel...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Jiahuan Wei, Daozhang Li, Haixia Long, Mei Han
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Subjects:	tumor-draining lymph nodes immune microenvironment immunosuppressive cells immunotherapy PD-L1/PD-1 CD8+ T cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1562797/full