Hypoxia-preconditioned bone marrow–derived mesenchymal stem cells protect neurons from cardiac arrest–induced pyroptosis

Cardiac arrest can lead to severe neurological impairment as a result of inflammation, mitochondrial dysfunction, and post-cardiopulmonary resuscitation neurological damage. Hypoxic preconditioning has been shown to improve migration and survival of bone marrow–derived mesenchymal stem cells and red...

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Bibliographic Details

Published in:	Neural Regeneration Research
Main Authors:	Xiahong Tang, Nan Zheng, Qingming Lin, Yan You, Zheng Gong, Yangping Zhuang, Jiali Wu, Yu Wang, Hanlin Huang, Jun Ke, Feng Chen
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2025-04-01
Subjects:	bone marrow–derived mesenchymal stem cells cardiac arrest cardiac resuscitation hypoxic preconditioning liver isoform of phosphofructokinase mitochondria neuroinflammation oxidative stress pyroptosis reactive oxygen species
Online Access:	https://journals.lww.com/10.4103/NRR.NRR-D-23-01922