Bromodomain-containing protein 4 activates androgen receptor transcription and promotes ovarian fibrosis in PCOS

Summary: Polycystic ovary syndrome (PCOS) is an endocrine disorder and the main cause of anovulatory infertility, in which persistent activation of androgen receptor (AR) due to aberrant acetylation modifications of transcription is a potential trigger; however, the precise mechanisms of AR activati...

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Bibliographic Details
Published in:Cell Reports
Main Authors: Daojuan Wang, Zhengquan Zhu, Yu Fu, Qiong Zhang, Yi Zhang, Tingyu Wang, Yajing Weng, Yanting Wen, Wangsen Cao, Gaojian Tao, Yong Wang
Format: Article
Language:English
Published: Elsevier 2023-09-01
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723011014