Optimization of lymphatic drug delivery system with carboplatin for metastatic lymph nodes

Abstract Systemic chemotherapy is a common method for treatment of metastatic lymph nodes (LNs), but it has low tissue selectivity and high toxicity. Lymphatic drug delivery system (LDDS) is a novel approach to treat and prevent LN metastases. In a previous study, it was found that the increase of o...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Miriu Miyatsu, Ariunbuyan Sukhbaatar, Radhika Mishra, Arunkumar Dorai, Shiro Mori, Tetsuya Kodama
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Subjects:
Lymph node metastasis
Chemotherapy
Carboplatin
Lymphatic drug delivery system
Osmotic pressure and viscosity
Online Access:https://doi.org/10.1038/s41598-025-99602-8

Internet

https://doi.org/10.1038/s41598-025-99602-8

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