NOVEL POTENTIAL HDAC INHIBITOR INDUCES CELL DIFFERENTIATION IN ACUTE MYELOID LEUKEMIA CELLS

Objective: Histone deacetylases (HDAC) are enzymes responsible for the deacetylation of histone proteins and play important roles in cell survival, cell proliferation, and gene expression in various types of cancers, including leukemias. High HDAC levels have been observed in hematological neoplasm...

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Bibliographic Details

Published in:	Hematology, Transfusion and Cell Therapy
Main Authors:	JAEG Carlos, LC Almeida, K Lima, MT Tavares, KB Waitman, LV Cost-Lotufo, R Paris-Filho, JA Machad-Neto
Format:	Article
Language:	English
Published:	Elsevier 2023-10-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2531137923006302