The Clinical and Laboratory Profiles of a Deletional α2-Globin Gene Polyadenylation Signal Sequence (AATAAA > AATA--) [HBA2:c.*93_*94delAA]: The Malaysian Experience

Poly A (AATAAA > AATA--) [HBA2:c.*93_*94delAA] is a rare α-variant reported in our population. It is caused by 2 bp deletion (--AA) in the α2 poly A sequence, leading to a significant α–thalassaemia phenotype. <b>Background/Objectives</b>: This study describes the haematological param...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Diagnostics
المؤلفون الرئيسيون:	Norafiza Mohd Yasin, Syahzuwan Hassan, Nur Aisyah Aziz, Faidatul Syazlin Abdul Hamid, Ezalia Esa, Ezzanie Suffya Zulkefli, Rohana Ghazali, Syirah Nazirah Tajuddin, Mohd Nazif Darawi, Yuslina Mat Yusoff, Cornelis L. Harteveld
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2025-05-01
الموضوعات:	non-deletional α-thalassaemia polyadenylation mutation AATA( > AA) Hb H disease
الوصول للمادة أونلاين:	https://www.mdpi.com/2075-4418/15/10/1284