Quercetin inhibits SARS-CoV-2 infection and prevents syncytium formation by cells co-expressing the viral spike protein and human ACE2

Abstract Background Several in silico studies have determined that quercetin, a plant flavonol, could bind with strong affinity and low free energy to SARS-CoV-2 proteins involved in viral entry and replication, suggesting it could block infection of human cells by the virus. In the present study, w...

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Bibliographic Details

Published in:	Virology Journal
Main Authors:	Annie V. Roy, Michael Chan, Logan Banadyga, Shihua He, Wenjun Zhu, Michel Chrétien, Majambu Mbikay
Format:	Article
Language:	English
Published:	BMC 2024-01-01
Subjects:	Quercetin SARS-CoV-2 Spike protein Human ACE2 HEK293 cells Syncytium formation
Online Access:	https://doi.org/10.1186/s12985-024-02299-w