Maf expression in B cells restricts reactive plasmablast and germinal center B cell expansion

Abstract Precise regulation of B cell differentiation is essential for an effective adaptive immune response. Here, we show that B cell development in mice with B cell-specific Maf deletion is unaffected, but marginal zone B cells, germinal centre B cells, and plasmablasts are significantly more fre...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Sophie Hillion, Anjelica Miranda, Christelle Le Dantec, Marina Boudigou, Laëtitia Le Pottier, Divi Cornec, Raul M. Torres, Roberta Pelanda
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Online Access:https://doi.org/10.1038/s41467-024-52224-6