Serum BDNF as a Potential Biomarker of Alzheimer's Disease: Verification Through Assessment of Serum, Cerebrospinal Fluid, and Medial Temporal Lobe Atrophy

There is an urgent need to establish blood biomarkers for Alzheimer's disease (AD). Although it has been speculated that brain-derived neurotrophic factor (BDNF) is associated with AD, whether it can be used as a blood biomarker has yet to be determined. We used serum, cerebrospinal fluid (CSF)...

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Bibliographic Details

Published in:	Frontiers in Neurology
Main Authors:	Yukiko Mori, Mayumi Tsuji, Tatsunori Oguchi, Kensaku Kasuga, Atsushi Kimura, Akinori Futamura, Azusa Sugimoto, Hideyo Kasai, Takeshi Kuroda, Satoshi Yano, Sotaro Hieda, Yuji Kiuchi, Takeshi Ikeuchi, Kenjiro Ono
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-04-01
Subjects:	Alzheimer's disease mild cognitive impairment blood biomarker BDNF medial temporal lobe atrophy
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2021.653267/full