Synthesis of Benzocycloalkanone-Based Michael Acceptors and Biological Activities as Antimalarial and Antitrypanosomal Agents

A series of benzocycloalkanone derivatives have been prepared and evaluated as antimalarial and antitrypanosomal agents. The compounds were obtained by direct coupling of preformed 4-substituted benzaldehyde and indanone or tetralone substitutes through aldol condensation of Claisen-Schmidt using so...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Ali Mijoba, Esteban Fernandez-Moreira, Nereida Parra-Giménez, Sandra Espinosa-Tapia, Zuleyma Blanco, Hegira Ramírez, Jaime E. Charris
Format:	Article
Language:	English
Published:	MDPI AG 2023-07-01
Subjects:	malaria <i>Plasmodium berghei</i> <i>Trypanosoma cruzi</i> benzocycloalkanone Michael Acceptors
Online Access:	https://www.mdpi.com/1420-3049/28/14/5569