Gene-expression signature predicts autoimmune toxicity in metastatic melanoma

Objectives To identify predictive gene-expression signatures for immune-related adverse events (irAEs) in patients with melanoma treated with anti-PD-1 inhibitors, in the adjuvant therapy (AT) and first-line therapy (FLT).Methods This retrospective study analyzed baseline whole-blood gene expression...

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Bibliographic Details

Published in:	Journal for ImmunoTherapy of Cancer
Main Authors:	Michael Bailey, Andrew White, Francesca Sparano, Alessandra Cesano, Mariaelena Capone, Corrado Caracò, Ester Simeone, Lucia Festino, Alfredo Budillon, Sarah Warren, Domenico Mallardo, Paolo A Ascierto, Vito Vanella, Ernesta Cavalcanti, Claudia Trojaniello, Maria Grazia Vitale, Margaret Ottaviano, Paolo Chiodini, Mario Fordellone, Bianca Arianna Facchini, Maria Ingenito, Caterina Costa, Rosaria De Filippi
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2025-07-01
Online Access:	https://jitc.bmj.com/content/13/7/e011315.full