The Role of Autophagy in iNKT Cell Development

CD1d-restricted invariant natural killer T (iNKT) cells are innate-like T cells that express an invariant T cell receptor (TCR) α-chain and recognize self and foreign glycolipid antigens. They can rapidly respond to agonist activation and stimulate an extensive array of immune responses. Thymic deve...

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Bibliographic Details
Published in:Frontiers in Immunology
Main Authors: Guan Yang, John P. Driver, Luc Van Kaer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Subjects:
invariant natural killer T cells
CD1d
autophagy
thymic development
metabolic switch
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02653/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02653/full

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