IFNα–IFITM1–ERK axis in corneal epithelial cell damage: implications for dry eye disease

Abstract Background Dry eye disease (DED) is a ubiquitous and intricate ocular condition featured by the disruption of tear film homeostasis and inflammation of the ocular surface. This study aimed to examine the mechanism of interferon-inducible transmembrane protein 1 (IFITM1) in dry eye disease (...

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Bibliographic Details

Published in:	European Journal of Medical Research
Main Authors:	Hongjuan Peng, Siyi Li, Guiling Zhao, Suyin Peng, Yanhua Pang
Format:	Article
Language:	English
Published:	BMC 2025-07-01
Subjects:	Dry eye disease Interferon-inducible transmembrane protein 1 Interferon-α Extracellular signal-regulated kinase Apoptosis
Online Access:	https://doi.org/10.1186/s40001-025-02757-3