NK cells and monocytes modulate primary HTLV-1 infection.

We investigated the impact of monocytes, NK cells, and CD8+ T-cells in primary HTLV-1 infection by depleting cell subsets and exposing macaques to either HTLV-1 wild type (HTLV-1WT) or to the HTLV-1p12KO mutant unable to infect replete animals due to a single point mutation in orf-I that inhibits it...

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Bibliographic Details
Published in:PLoS Pathogens
Main Authors: Ramona Moles, Sarkis Sarkis, Veronica Galli, Maria Omsland, Maria Artesi, Massimiliano Bissa, Katherine McKinnon, Sophia Brown, Vincent Hahaut, Robyn Washington-Parks, Joshua Welsh, David J Venzon, Anna Gutowska, Melvin N Doster, Matthew W Breed, Kristin E Killoran, Joshua Kramer, Jennifer Jones, Marcin Moniuszko, Anne Van den Broeke, Cynthia A Pise-Masison, Genoveffa Franchini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-04-01
Online Access:https://doi.org/10.1371/journal.ppat.1010416

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https://doi.org/10.1371/journal.ppat.1010416

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