Somites are a source of nephron progenitors in zebrafish

Abstract For over a century it has been believed that the vertebrate kidney arises exclusively from the intermediate mesoderm. Here, we overturn this paradigm by demonstrating that some nephrons, the functional units of the kidney, originate from the somites— blocks of paraxial mesoderm best known f...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Zhenzhen Peng, Thitinee Vanichapol, Phong Dang Nguyen, Hao-Han George Chang, Katrinka M. Kocha, Lori L. O’Brien, Peter D. Currie, Peng Huang, Alan J. Davidson
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Online Access:https://doi.org/10.1038/s41467-025-62259-y