Failure to Identify Somatic Mutations in Monozygotic Twins Discordant for Schizophrenia by Whole Exome Sequencing

Background: Schizophrenia (SCZ) is a severe, debilitating, and complex psychiatric disorder with multiple causative factors. An increasing number of studies have determined that rare variations play an important role in its etiology. A somatic mutation is a rare form of genetic variation that occurs...

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Bibliographic Details

Published in:	Chinese Medical Journal
Main Authors:	Nan Lyu, Li-Li Guan, Hong Ma, Xi-Jin Wang, Bao-Ming Wu, Fan-Hong Shang, Dan Wang, Hong Wen, Xin Yu
Format:	Article
Language:	English
Published:	Wolters Kluwer 2016-01-01
Subjects:	Monozygotic Twins; Schizophrenia; Somatic Mutation; Whole Exome Sequencing
Online Access:	http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=6;spage=690;epage=695;aulast=Lyu