TRIM33 loss reduces androgen receptor transcriptional output and H2BK120 ubiquitination

Abstract The Androgen Receptor (AR) is a ligand-dependent transcription factor that drives prostate cancer development and progression. Although, a detailed effect on AR biology has been described for a number of interacting proteins, many AR coregulators remain to be characterized in relation to th...

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Bibliographic Details

Published in:	Communications Biology
Main Authors:	Nils Eickhoff, Janina Janetzko, Nuno Padrão, Sebastian Gregoricchio, Joseph C. Siefert, Liesbeth Hoekman, Simon Linder, Onno Bleijerveld, Andries M. Bergman, Wilbert Zwart
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-07-01
Online Access:	https://doi.org/10.1038/s42003-025-08449-2