Characterization of pulmonary vascular remodeling and MicroRNA-126-targets in COPD-pulmonary hypertension

Abstract Background Despite causing increased morbidity and mortality, pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) patients (COPD-PH) lacks treatment, due to incomplete understanding of its pathogenesis. Hypertrophy of pulmonary arterial walls and pruning of the micro...

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Bibliographic Details

Published in:	Respiratory Research
Main Authors:	Khushboo Goel, Nicholas Egersdorf, Amar Gill, Danting Cao, Scott D. Collum, Soma S. Jyothula, Howard J. Huang, Maor Sauler, Patty J. Lee, Susan Majka, Harry Karmouty-Quintana, Irina Petrache
Format:	Article
Language:	English
Published:	BMC 2022-12-01
Subjects:	Chronic obstructive pulmonary disease Emphysema Endothelial cells Smoking Pulmonary vascular remodeling Group 3 pulmonary hypertension
Online Access:	https://doi.org/10.1186/s12931-022-02267-4