The Coming Age of Antisense Oligos for the Treatment of Hepatic Ischemia/Reperfusion (IRI) and Other Liver Disorders: Role of Oxidative Stress and Potential Antioxidant Effect

Imbalances in the redox state of the liver arise during metabolic processes, inflammatory injuries, and proliferative liver disorders. Acute exposure to intracellular reactive oxygen species (ROS) results from high levels of oxidative stress (OxS) that occur in response to hepatic ischemia/reperfusi...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Siyuan Yao, Aanchal Kasargod, Richard Chiu, Taylor R. Torgerson, Jerzy W. Kupiec-Weglinski, Kenneth J. Dery
Format:	Article
Language:	English
Published:	MDPI AG 2024-05-01
Subjects:	antisense oligonucleotides CEACAM1 hepatocytes inflammation ischemia-reperfusion injury Kupffer cells
Online Access:	https://www.mdpi.com/2076-3921/13/6/678