Comprehensive analysis of lipid nanoparticle formulation and preparation for RNA delivery

Nucleic acid-based therapeutics are a common approach that is increasingly popular for a wide spectrum of diseases. Lipid nanoparticles (LNPs) are promising delivery carriers that provide RNA stability, with strong transfection efficiency, favorable and tailorable pharmacokinetics, limited toxicity,...

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Bibliographic Details

Published in:	International Journal of Pharmaceutics: X
Main Authors:	Md. Anamul Haque, Archana Shrestha, Constantinos M. Mikelis, George Mattheolabakis
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Subjects:	Lipid nanoparticles mRNA siRNA Transfection Microfluidics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590156724000550