Cuproptosis engages in c-Myc-mediated breast cancer stemness

Abstract Background Intra-tumoral heterogeneity (ITH) is a distinguished hallmark of cancer, and cancer stem cells (CSCs) contribute to this malignant characteristic. Therefore, it is of great significance to investigate and even target the regulatory factors driving intra-tumoral stemness. c-Myc is...

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Bibliographic Details

Published in:	Journal of Translational Medicine
Main Authors:	Runtian Wang, Kun Xu, Qin Chen, Qin Hu, Jian Zhang, Xiaoxiang Guan
Format:	Article
Language:	English
Published:	BMC 2023-06-01
Subjects:	Intra-tumoral heterogeneity c-Myc Cancer stem cell Copper-induced cell death Cuproptosis Tumor microenvironment
Online Access:	https://doi.org/10.1186/s12967-023-04204-5