Biochemistry and physiology of voltage-gated calcium channel trafficking: a target for gabapentinoid drugs

Voltage-gated calcium channels are multi-pass transmembrane proteins that have key features that are essential for their correct function. For example, the concerted movement of the voltage sensor domains in response to depolarization is required to ensure the channels open over a particular range o...

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Bibliographic Details
Published in:Open Biology
Main Author: Annette C. Dolphin
Format: Article
Language:English
Published: The Royal Society 2025-07-01
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.250013