SMYD3 associates with the NuRD (MTA1/2) complex to regulate transcription and promote proliferation and invasiveness in hepatocellular carcinoma cells

Abstract Background SMYD3, a member of the SET and MYND domain-containing (SMYD) family, is a histone methyltransferase (HMT) and transcription factor that plays an important role in transcriptional regulation in human carcinogenesis. Results Using affinity purification and mass spectrometry assays...

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發表在:	BMC Biology
Main Authors:	Yang Yang, Rongfang Qiu, Siyu Zhao, Lin Shen, Bufu Tang, Qiaoyou Weng, Ziwei Xu, Liyun Zheng, Weiqian Chen, Gaofeng Shu, Yajie Wang, Zhongwei Zhao, Minjiang Chen, Jiansong Ji
格式:	Article
語言:	英语
出版:	BMC 2022-12-01
主題:	SMYD3 Hepatocellular carcinoma NuRD complex IGFBP4 Metastasis
在線閱讀:	https://doi.org/10.1186/s12915-022-01499-6