Improvement of NK Cell Cytotoxicity in Reconstituting NK Cells after Allogeneic Stem Cell Transplantation by Blocking NKG2A Checkpoint

Background: One cause of tumor relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the alteration of the graft-versus-tumor effect of early reconstituting natural killer (NK) cells due to overexpression of the NKG2A inhibitory receptor. This study aims to determine the ef...

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Bibliographic Details

Published in:	Middle East Journal of Cancer
Main Authors:	Mohammed Taha, Cyril Fauriat
Format:	Article
Language:	English
Published:	Shiraz University of Medical Sciences 2023-10-01
Subjects:	natural killer cells monalizumab nkg2a cell cytotoxicity allogeneic hematopoietic stem cell transplantation
Online Access:	https://mejc.sums.ac.ir/article_49288_c34d602f3ba78ba602d07e535ffb28c8.pdf