Pichia pastoris versus Saccharomyces cerevisiae: a case study on the recombinant production of human granulocyte-macrophage colony-stimulating factor

Abstract Background Recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) is a glycoprotein that has been approved by the FDA for the treatment of neutropenia and leukemia in combination with chemotherapies. Recombinant hGM-CSF is produced industrially using the baker’s yeast...

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Bibliographic Details
Published in:BMC Research Notes
Main Authors: Anh-Minh Tran, Thanh-Thao Nguyen, Cong-Thuan Nguyen, Xuan-Mai Huynh-Thi, Cao-Tri Nguyen, Minh-Thuong Trinh, Linh-Thuoc Tran, Stephanie P. Cartwright, Roslyn M. Bill, Hieu Tran-Van
Format: Article
Language:English
Published: BMC 2017-04-01
Subjects:
S. cerevisiae
P. pastoris
rhGM-CSF
Fermentation
Bioactivity
TF-1 cell
Online Access:http://link.springer.com/article/10.1186/s13104-017-2471-6

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http://link.springer.com/article/10.1186/s13104-017-2471-6

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