A DGCR8-Independent Stable MicroRNA Expression Strategy Reveals Important Functions of miR-290 and miR-183–182 Families in Mouse Embryonic Stem Cells

Summary: Dgcr8 knockout cells provide a great means to understand the function of microRNAs (miRNAs) in vitro and in vivo. Current strategies to study miRNA function in Dgcr8 knockout cells depend on transient transfection of chemically synthesized miRNA mimics, which is costly and not suitable for...

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發表在:	Stem Cell Reports
Main Authors:	Xi-Wen Wang, Jing Hao, Wen-Ting Guo, Le-Qi Liao, Si-Yue Huang, Xiangpeng Guo, Xichen Bao, Miguel A. Esteban, Yangming Wang
格式:	Article
語言:	英语
出版:	Elsevier 2017-11-01
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2213671117304113