Therapeutic Applications of Azanucleoside Analogs as DNA Demethylating Agents

Azanucleosides, such as 5-azacytidine and decitabine, are DNA demethylating agents used in the treatment of acute myeloid leukemia and myelodysplastic syndromes. Researchers continue to explore their utility in the treatment of other hematologic and solid tumors. Based on the capacity of the compoun...

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Bibliographic Details
Published in:Epigenomes
Main Authors: Fallon Gallimore, Tamer E. Fandy
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Subjects:
Online Access:https://www.mdpi.com/2075-4655/7/3/12