HMGB1 in Systemic Lupus Erythematosus

The high-mobility group box 1 (HMGB1) has been shown to exert proinflammatory effects on many cells of the innate immune system. Originally identified as a nuclear protein, HMGB1 has been found to play an important role in mediating inflammation when released from apoptotic or necrotic cells as a da...

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Bibliographic Details
Published in:Frontiers in Immunology
Main Authors: Tianye Liu, Myoungsun Son, Betty Diamond
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01057/full