Integrating functional data to prioritize causal variants in statistical fine-mapping studies.

Standard statistical approaches for prioritization of variants for functional testing in fine-mapping studies either use marginal association statistics or estimate posterior probabilities for variants to be causal under simplifying assumptions. Here, we present a probabilistic framework that integr...

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書誌詳細

出版年:	PLoS Genetics
主要な著者:	Gleb Kichaev, Wen-Yun Yang, Sara Lindstrom, Farhad Hormozdiari, Eleazar Eskin, Alkes L Price, Peter Kraft, Bogdan Pasaniuc
フォーマット:	論文
言語:	英語
出版事項:	Public Library of Science (PLoS) 2014-10-01
オンライン･アクセス:	http://europepmc.org/articles/PMC4214605?pdf=render