Extracellular Ubiquitin Enhances Autophagy and Inhibits Mitochondrial Apoptosis Pathway to Protect Neurons Against Spinal Cord Ischemic Injury via CXCR4

Objective Neuronal apoptosis is considered to be a critical process in spinal cord injury (SCI). Despite growing evidence of the antiapoptotic, anti-inflammatory, and modulation of ischemic injury tolerance effects of extracellular ubiquitin (eUb), existing studies have paid less attention to the im...

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Bibliographic Details

Published in:	Neurospine
Main Authors:	Hao Feng, Dehui Chen, Huina Chen, Dingwei Wu, Dandan Wang, Zhengxi Yu, Linquan Zhou, Zhenyu Wang, Wenge Liu
Format:	Article
Language:	English
Published:	Korean Spinal Neurosurgery Society 2025-03-01
Subjects:	spinal cord injury extracellular ubiquitin cxcr4 autophagy mitochondrial apoptosis pathway
Online Access:	http://e-neurospine.org/upload/pdf/ns-2448878-439.pdf