Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy

Abstract Bone is the most common site of breast cancer metastasis, yet understanding the intricate mechanisms and potential therapeutic targets remains nascent. Here it is reported that breast cancer establishes a hyperglycemic bone pre‐metastatic niche before migrating to bone tissue and further en...

Full description

Bibliographic Details

Published in:	Advanced Science
Main Authors:	Jianxin Ye, Peng Hu, Rui Zhang, Lei Zhou, Zonghua Luo, Yanan Chen, Shengzhe Ruan, Mengyi Zhu, Huaze Ding, Yike Qian, Yan Xing, Tong Meng, Changping Wang, Dianwen Song
Format:	Article
Language:	English
Published:	Wiley 2025-10-01
Subjects:	bone pre‐metastatic niches engineered enzyme glucose metabolism selective chemotherapy self‐amplifying starvation
Online Access:	https://doi.org/10.1002/advs.202504924