Protective immunity induced by DNA vaccine containing TgGRA35, TgGRA42, and TgGRA43 against Toxoplasma gondii infection in Kunming mice

BackgroundToxoplasma gondii can cause congenital infection and abortion in humans and warm-blooded animals. T. gondii dense granule proteins, GRA35, GRA42, and GRA43, play a critical role in the establishment of chronic infection. However, their potential to induce protective immunity against T. gon...

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Bibliographic Details

Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Youbo Shi, Jianbing Li, Weili Yang, Jia Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-10-01
Subjects:	Toxoplasma gondii GRA35 GRA42 GRA43 DNA vaccine protective immunity
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2023.1236130/full