Polydopamine-based nano-protectant for prolonged boar semen preservation by eliminating ROS and regulating protein phosphorylation via D2DR-mediated cAMP/PKA signaling pathway

Abstract Introduction Preservation of porcine semen is essential for artificial insemination and genetic improvement in pig breeding programs. However, the overproduction of reactive oxygen species (ROS) and lower levels of protein phosphorylation emerge as two challenges during semen preservation....

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Bibliographic Details

Published in:	Journal of Nanobiotechnology
Main Authors:	Lirui Wang, Manyi Xiong, Jian Zhang, Sisi Li, Sheng Ma, Shengyao Jiang, Yanping Jiang, Xinhong Li
Format:	Article
Language:	English
Published:	BMC 2025-02-01
Subjects:	Semen preservation Polydopamine nanoparticles ROS Protein phosphorylation D2DR
Online Access:	https://doi.org/10.1186/s12951-025-03215-2