Polyfunctional CD4+ T Cells As Targets for Tuberculosis Vaccination

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of morbidity and mortality worldwide, despite the widespread use of the only licensed vaccine, Bacille Calmette Guerin (BCG). Eradication of TB will require a more effective vaccine, yet evaluation of new vaccine...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Deborah A. Lewinsohn, David M. Lewinsohn, Thomas J. Scriba
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-10-01
Subjects:	T-cell immunity CD4+ T cells vaccine-induced immunity tuberculosis vaccine protective immunity
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01262/full