Heterogeneity of Intestinal Tissue Eosinophils: Potential Considerations for Next-Generation Eosinophil-Targeting Strategies

Eosinophils are implicated in the pathophysiology of a spectrum of eosinophil-associated diseases, including gastrointestinal eosinophilic diseases (EGIDs). Biologics that target the IL-5 pathway and are intended to ablate eosinophils have proved beneficial in severe eosinophilic asthma and may offe...

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Bibliographic Details

Published in:	Cells
Main Authors:	Joanne C. Masterson, Calies Menard-Katcher, Leigha D. Larsen, Glenn T. Furuta, Lisa A. Spencer
Format:	Article
Language:	English
Published:	MDPI AG 2021-02-01
Subjects:	eosinophil eosinophilic gastrointestinal diseases biologics eosinophil sub-phenotypes
Online Access:	https://www.mdpi.com/2073-4409/10/2/426