Notch hyper-activation drives trans-differentiation of hESC-derived endothelium

During development, endothelial cells (EC) display tissue-specific attributes that are unique to each vascular bed, as well as generic signaling mechanisms that are broadly applied to create a patent circulatory system. We have previously utilized human embryonic stem cells (hESC) to generate tissue...

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發表在:	Stem Cell Research
Main Authors:	David Reichman, Limor Man, Laura Park, Raphael Lis, Jeannine Gerhardt, Zev Rosenwaks, Daylon James
格式:	Article
語言:	英语
出版:	Elsevier 2016-09-01
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S1873506116301209