Liver X Receptor Regulation of Glial Cell Functions in the CNS

In this review, we discuss the role of liver X receptors (LXRs) in glial cells (microglia, oligodendrocytes and astrocytes) in the central nervous system (CNS). LXRs are oxysterol-activated nuclear receptors that, in adults, regulate genes involved in cholesterol homeostasis, the modulation of infla...

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Bibliographic Details
Published in:Biomedicines
Main Authors: Xiaoyu Song, Wanfu Wu, Margaret Warner, Jan-Åke Gustafsson
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Subjects:
Online Access:https://www.mdpi.com/2227-9059/10/9/2165