Typical and Atypical Antipsychotic Drugs Increase Extracellular Histamine Levels in the Rat Medial Prefrontal Cortex: Contribution of Histamine H1 Receptor Blockade
Atypical antipsychotics such as clozapine and olanzapine have been shown to enhance histamine turnover and this effect has been hypothesized to contribute to their improved therapeutic profile compared to typical antipsychotics. In the present study, we examined the effects of antipsychotic drugs on...
| Published in: | Frontiers in Psychiatry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2012-05-01
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpsyt.2012.00049/full |