Understanding the Difference between Risk of Bias and Concerns Regarding Applicability Using QUADAS-2: A Methodological Review

Introduction: Diagnostic test accuracy (DTA) systematic reviews bring together findings from DTA studies to summarise the accuracy of a diagnostic test. Studies included in a DTA review should be assessed for risk of bias and applicability concerns, because a review of biased studies, or studies th...

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Bibliographic Details

Published in:	Epidemiology, Biostatistics and Public Health
Main Authors:	Anne W.S. Rutjes, Alessio Lachi, Jude Holmes, Eve Tomlinson, Mariska M. G. Leeflang, Penny Whiting, Sue Mallett, Clare Davenport
Format:	Article
Language:	English
Published:	Milano University Press 2025-09-01
Online Access:	https://riviste.unimi.it/index.php/ebph/article/view/29261