The diverse dependence of galectin-1 and -8 on multivalency for the modulation of FGFR1 endocytosis

Abstract Fibroblast growth factor receptor 1 (FGFR1) is a N-glycosylated cell surface receptor tyrosine kinase, which upon recognition of specific extracellular ligands, fibroblast growth factors (FGFs), initiates an intracellular signaling. FGFR1 signaling ensures homeostasis of cells by fine-tunin...

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Bibliographic Details
Published in:Cell Communication and Signaling
Main Authors: Dominika Żukowska, Aleksandra Chorążewska, Krzysztof Ciura, Aleksandra Gędaj, Marta Kalka, Marta Poźniak, Natalia Porębska, Łukasz Opaliński
Format: Article
Language:English
Published: BMC 2024-05-01
Subjects:
FGFR1
Galectins
Multivalency
Signaling
Endocytosis
CME
Online Access:https://doi.org/10.1186/s12964-024-01661-3

Internet

https://doi.org/10.1186/s12964-024-01661-3

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