STAT3 Promotes Invasion and Aerobic Glycolysis of Human Oral Squamous Cell Carcinoma via Inhibiting FoxO1

Signal transducer and activator of transcription 3 (STAT3), a previously accepted tumor-promoting protein in various malignancies, plays a key role in the process of cancer glycolysis. However, the role and potential mechanism of STAT3 in aerobic glycolysis and progression of oral squamous cell carc...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Min Zheng, Ming-xin Cao, Xiang-hua Yu, Li Li, Ke Wang, Sha-sha Wang, Hao-fan Wang, Ya-Jie Tang, Ya-ling Tang, Xin-hua Liang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-11-01
Subjects:	STAT3 FoxO1 aerobic glycolysis EMT OSCC
Online Access:	https://www.frontiersin.org/article/10.3389/fonc.2019.01175/full