Epithelial Dual Oxidase 2 Shapes the Mucosal Microbiome and Contributes to Inflammatory Susceptibility

Reactive oxygen species (ROS) are highly reactive molecules formed from diatomic oxygen. They act as cellular signals, exert antibiotic activity towards invading microorganisms, but can also damage host cells. Dual oxidase 2 (DUOX2) is the main ROS-producing enzyme in the intestine, regulated by cue...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Juan Camilo Castrillón-Betancur, Víctor Alonso López-Agudelo, Nina Sommer, Sven Cleeves, Joana Pimenta Bernardes, Saskia Weber-Stiehl, Philip Rosenstiel, Felix Sommer
Format:	Article
Language:	English
Published:	MDPI AG 2023-10-01
Subjects:	inflammation DUOX2 ROS microbiome
Online Access:	https://www.mdpi.com/2076-3921/12/10/1889